| Opponent | W | L | T | Pct. | Last F&M Win | Last Opp. Win | Streak |
| Albright | 18 | 1 | 2 | .900 | 2007 | 1985 | 8 |
| Alvernia | 9 | 0 | 0 | 1.000 | 2015 | 9 | |
| Babson | 0 | 1 | 0 | .000 | 2016 | -1 | |
| Beaver | 1 | 0 | 0 | 1.000 | 1996 | 1 | |
| Bloomsburg | 2 | 8 | 0 | .200 | 1992 | 1994 | -2 |
| Brockport | 0 | 1 | 0 | .000 | 1980 | -1 | |
| Bryn Mawr | 22 | 0 | 2 | .958 | 2016 | 22 | |
| Bucknell | 0 | 3 | 0 | .000 | 1984 | -3 | |
| Cabrini | 2 | 0 | 0 | 1.000 | 2015 | 2 | |
| Catholic | 6 | 5 | 0 | .545 | 2004 | 2003 | 1 |
| College of NJ | 1 | 1 | 0 | .500 | 2016 | 1981 | 1 |
| Cortland St. | 3 | 6 | 0 | .333 | 2011 | 1996 | 1 |
| CW Post | 1 | 0 | 0 | 1.000 | 2005 | 1 | |
| Delaware | 0 | 8 | 1 | .056 | 1978 (tie) | 1980 | -3 |
| Delaware Valley | 1 | 0 | 0 | 1.000 | 1980 | 1 | |
| Denison | 3 | 0 | 0 | 1.000 | 1983 | 1982 | 1 |
| DeSales | 1 | 0 | 0 | 1.000 | 2004 | 1 | |
| Dickinson | 38 | 9 | 2 | .796 | 2016 | 2007 | 10 |
| Drew | 6 | 8 | 0 | .429 | 2005 | 2003 | 2 |
| Eastern | 8 | 2 | 0 | .800 | 2016 | 2012 | 4 |
| Eastern Mennonite | 7 | 10 | 0 | .411 | 2010 | 2008 | 2 |
| Elizabethtown | 24 |
20 | 3 | .543 | 2016 | 2012 | 4 |
| FDU-Madison | 0 | 1 | 0 | .000 | -1 | ||
| Gettysburg | 26 |
21 | 3 | .550 | 2016 | 2010 | 6 |
| Goucher | 1 | 1 | 0 | .500 | 1996 | 1995 | 1 |
| Hartwick | 1 | 1 | 0 | .500 | 1981 | 1996 | -1 |
| Haverford | 28 |
7 | 1 | .792 | 2016 | 2010 | 9 |
| Ithaca | 1 | 9 | 0 | .100 | 1987 | 1991 | -4 |
| Immaculata | 4 | 0 | 0 | 1.000 | 2014 | 4 | |
| Johns Hopkins | 13 | 22 | 1 | .375 | 2016 | 2010 | 6 |
| Johnson St. | 1 | 0 | 0 | 1.000 | 1979 | 1 | |
| Juniata | 12 | 4 | 0 | .750 | 2001 | 1999 | 2 |
| Kean | 0 | 1 | 0 | 1.000 | 2005 | -1 | |
| Kenyon | 0 | 1 | 0 | .000 | 2006 | -1 | |
| King's | 1 | 0 | 0 | 1.000 | 2016 | 1 | |
| Kutztown | 1 | 0 | 0 | 1.000 | 1973 | 1 | |
| Lafayette | 2 | 3 | 1 | .417 | 1980 | 1983 | -3 |
| Lancaster Bible | 1 | 0 | 0 | 1.000 | 1973 | 1 | |
| Lebanon Valley | 16 | 22 | 3 | .427 | 2013 | 2011 | 1 |
| Lehigh | 1 | 1 | 1 | .500 | 1979 | 1977 | 1 |
| Lynchburg | 2 | 2 |
0 | .500 | 2008 |
2011 |
-1 |
| Manhattanvillle | 2 | 0 | 0 | 1.000 | 2003 | 2 | |
| Maryland | 0 | 1 | 0 | .000 | 1978 | -1 | |
| Mary Washington | 6 | 8 | 0 | .429 | 2016 | 2007 | 3 |
| McDaniel | 27 | 14 | 1 | .655 | 2016 | 2008 | 8 |
| Messiah | 7 | 21 | 4 | .281 | 2014 | 2016 | -2 |
| Middlebury | 0 | 2 | 0 | .000 | 2015 | -2 | |
| Millersville | 4 | 15 | 2 | .238 | 1992 | 2001 | -8 |
| Misericordia | 2 | 0 | 0 | 1.000 | 2013 | 2 | |
| Montclair | 0 | 1 | 0 | .000 | 2004 | -1 | |
| Mt. St. Mary's | 2 | 0 | 0 | 1.000 | 1982 | 2 | |
| Muhlenberg | 19 | 7 | 1 | .722 | 2016 | 2016 | 1 |
| Neuman | 1 | 0 | 0 | 1.000 | 2009 | 1 | |
| Notre Dame | 0 | 1 | 0 | .000 | 1985 | -1 | |
| Oneonta | 2 | 0 | 0 | 1.000 | 1980 | 1979 | 1 |
| Penn | 0 | 5 | 1 | .083 | 1981 | -4 | |
| Penn St. | 0 | 0 | 1 | .500 | 0 | ||
| Phila. Textile | 3 | 0 | 0 | 1.000 | 1988 | 3 | |
| Princeton | 0 | 2 | 1 | .167 | 1979 | 1981 | -1 |
| Regis (Mass.) | 1 | 0 | 0 | 1.000 | 2014 | 1 | |
| Rhodes | 1 | 0 | 0 | 1.000 | 2012 | 1 | |
| Roanoke | 1 | 0 | 0 | 1.000 | 2008 | 1 | |
| Rowan | 5 | 1 | 0 | .833 | 2016 | 1978 | 5 |
| Salem St. | 1 | 0 | 0 | 1.000 | 1982 | 1 | |
| Salisbury St. | 0 | 2 | 1 | .167 | 1992 | -2 | |
| Scranton | 3 | 0 | 0 | 1.000 | 1985 | 2 | |
| Shippensburg | 2 | 9 | 2 | .231 | 1980 | 1993 | -7 |
| St. Lawrence | 1 | 0 | 0 | 1.000 | 2010 | 1 | |
| St. Mary's (Md.) | 1 | 0 | 0 | 1.000 | 2014 | 1 | |
| Susquehanna | 1 |
3 | 0 | .250 | 2011 |
1997 | 1 |
| Swarthmore | 16 | 10 | 1 | .611 | 2016 | 2007 | 9 |
| Ursinus | 7 | 27 | 0 | .206 | 2016 |
2016 | -1 |
| Villa Julie | 3 | 0 | 0 | 1.000 | 2004 | 3 | |
| V.C.U. | 0 | 1 | 0 | .000 | 1983 | -1 | |
| Washington (Md.) | 13 | 11 | 0 | .542 | 2016 | 2010 | 6 |
| Wesley | 1 | 0 | 0 | 1.000 | 1997 | 1 | |
| West Chester | 0 | 2 | 0 | .000 | 1974 | -2 | |
| Widener | 7 | 0 | 1 | .938 | 1987 | 1984(tie) | 3 |
| Wilkes | 3 | 2 | 0 | .600 | 1983 | 1979 | 3 |
| William Smith | 1 | 5 | 0 | .166 | 1985 | 2010 | -4 |
| Wilson | 4 | 0 | 0 | 1.000 | 1977 | 4 | |
| York | 23 | 10 | 0 | .697 | 2010 | 2016 | -2 |
| Total | 434 | 340 |
36 | .558 |